Article
Keratin5-cytoskeleton-BMP4 network regulates cell phenotype conversions during cardiac regeneration.
Experimental cell research - 1 Sept 2022
Wang Xuelong, Guo Huiping, Yu Feifei, Zhang Hui, Peng Ying, Wang Chenghui, Wei Gang, Yan Jizhou
Abstract excerpt
The reconstruction of a blood supply system and myocardial recovery from inflamamtory reactions in the infract zone remains a challenge in cardiac regeneration after myocardial infarction. Here, we observed that the local myocardial cells and the clotted blood cells undergo cellular remodeling via cytoplasmic exocytosis and nuclear reorganization in zebrafish hearts after resection of the ventricular apex. The...
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