Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection With accumulation of mutations in a patient with poorly controlled Human Immunodeficiency Virus infection.

doi:10.1093/cid/ciac548

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Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection With accumulation of mutations in a patient with poorly controlled Human Immunodeficiency Virus infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 8 Feb 2023

Maponga Tongai G, Jeffries Montenique, Tegally Houriiyah, Sutherland Andrew, Wilkinson Eduan, Lessells Richard J, Msomi Nokukhanya, van Zyl Gert, de Oliveira Tulio, Preiser Wolfgang

Abstract excerpt

A 22-year-old woman with uncontrolled advanced human immunodeficiency virus (HIV) infection was persistently infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) beta variant for 9 months, the virus accumulating >20 additional mutations. Antiretroviral therapy suppressed HIV and cleared SARS-CoV-2 within 6 to 9 weeks. Increased vigilance is warranted to benefit affected individuals and...

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Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection With accumulation of mutations in a patient with poorly controlled Human Immunodeficiency Virus infection.

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