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Decrease of MtDNA copy number affects mitochondrial function and involves in the pathological consequences of ischaemic stroke

5 Jul 2022

Abstract excerpt

The mtDNA copy number can affect the function of mitochondria and play an important role in the development of diseases. However, there are few studies on the mechanism of mtDNA copy number variation and its effects in IS. The specific mechanism of mtDNA copy number variation is still unclear. In this study, mtDNA copy number of 101 IS patients and 101 normal controls were detected by qRT-PCR, the effect of...

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PMID: 35791521
DOI: 10.1111/jcmm.17262

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