Article
New Strategies in Sarcoma: Linking Genomic and Immunotherapy Approaches to Molecular Subtype
2 Sept 2015
Abstract excerpt
There are more than 100 sarcoma subtypes, each uncommon and diagnostically challenging. Conventional chemotherapy has little benefit for most soft-tissue sarcomas; new treatment strategies are needed. Multiple recent genomic studies have provided detailed insights into sarcoma biology, including more accurate classification by molecular subtype, identification of recurrent mutations in oncogenic pathways, and...
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