Article
Context-aware deconvolution of cell-cell communication with Tensor-cell2cell.
Nature communications - 27 Jun 2022
Armingol Erick, Baghdassarian Hratch M, Martino Cameron, Perez-Lopez Araceli, Aamodt Caitlin, Knight Rob, Lewis Nathan E
Abstract excerpt
Cell interactions determine phenotypes, and intercellular communication is shaped by cellular contexts such as disease state, organismal life stage, and tissue microenvironment. Single-cell technologies measure the molecules mediating cell-cell communication, and emerging computational tools can exploit these data to decipher intercellular communication. However, current methods either disregard cellular context...
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