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Impacts of RNA Mobility Signals on Virus Induced Somatic and Germline Gene Editing

9 Jun 2022

Abstract excerpt

Viral vectors are being engineered to deliver CRISPR/Cas9 components systemically in plants to induce somatic or heritable site-specific mutations. It is hypothesized that RNA mobility signals facilitate entry of viruses or single guide RNAs (sgRNAs) into the shoot apical meristem where germline mutations can occur. Our objective was to understand the impact of RNA mobility signals on virus-induced somatic and...

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PMID: 35755451
DOI: 10.3389/fgeed.2022.925088

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