Article
Nontransgenic genome modification in plant cells.
Plant physiology - 1 Nov 2010
Marton Ira, Zuker Amir, Shklarman Elena, Zeevi Vardit, Tovkach Andrey, Roffe Suzy, Ovadis Marianna, Tzfira Tzvi, Vainstein Alexander
Abstract excerpt
Zinc finger nucleases (ZFNs) are a powerful tool for genome editing in eukaryotic cells. ZFNs have been used for targeted mutagenesis in model and crop species. In animal and human cells, transient ZFN expression is often achieved by direct gene transfer into the target cells. Stable transformati...
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