High-efficiency, transgene-free plant genome editing by viral delivery of an engineered TnpB

Abstract excerpt

Genome editing has revolutionized plant biology research. However, efficient and straightforward delivery of editing reagents remains a major challenge. Viral delivery systems can address these issues, but CRISPR-Cas nucleases are often too large for viral vectors. Recently, smaller editors like TnpBs have been identified, but wild-type TnpBs are significantly less active than commonly used Cas9 nucleases. Here, w...

Topics

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• CRISPR-Cas Systems
• Gene Editing
• Genome, Plant
• Genotype
• Plant Breeding
• Plants
• Plants, Genetically Modified
• RNA Viruses

Identifiers and source

Literature Corpus work

593abd67-7e3f-5440-a1b8-c3a8bbdc8c07

DOI

10.64898/2025.12.05.692691