Article
Epigenetic/genetic variations in CG-rich elements of immune-related genes contribute to food allergy development during childhood.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jun 2022
Kostara Maria, Chondrou Vasiliki, Fotopoulos Vassilis, Sgourou Argyro, Tsabouri Sophia
Abstract excerpt
BACKGROUND: Genetic areas of FOXP3 TSDR, human leukocyte antigen-G (HLA-G) upstream of CpG island 96, CpG41 and CpG73 islands of the HLA-DRB1 and HLA-DQB1 genes respectively, previously documented to display immune-modulatory properties, were subjected to epigenetic/genetic analysis to assess their influence in IgE-mediated food allergy (FA) development in children. METHODS: Sixty-four orally challenged and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.