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Article

Association study of MMP8 gene in osteoarthritis.

Connective tissue research - 1 Jan 2016

Näkki Annu, Rodriguez-Fontenla Cristina, Gonzalez Antonio, Harilainen Arsi, Leino-Arjas Päivi, Heliövaara Markku, Eriksson Johan G, Tallroth Kaj, Videman Tapio, Kaprio Jaakko, Saarela Janna, Kujala Urho M

Abstract excerpt

OBJECTIVES: Osteoarthritis (OA) is a joint disease common in the elderly. There is a prior functional evidence for different matrix metalloproteinases (MMPs), such as MMP8 and MMP9, having a role in the breakdown of cartilage extracellular matrix in OA. Thus, we analyzed whether the common genetic variants of MMP8 and MMP9 contribute to the risk of OA. MATERIALS AND METHODS: In total, 13 common tagging...

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Identifiers

PMID: 26577236
DOI: 10.3109/03008207.2015.1099636

Genes

MMP8
MMP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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