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Evolutionary history and spread of the Mycobacterium tuberculosis Latin American and Mediterranean (L4.3/LAM) sublineage, Tunisia.

Tuberculosis (Edinburgh, Scotland) - 1 Jan 2023

Skhairia Mohamed Amine, Dekhil Naira, Mardassi Helmi

Abstract excerpt

BACKGROUND: To infer the origin and spread of the Mycobacterium tuberculosis Latin American and Mediterranean (L4.3/LAM) sublineage in a Mediterranean country, Tunisia, where it predominates. METHODS: We combined Bayesian (STRUCTURE) and maximum likelihood (MIGRAINE) estimation approaches based on a global 24-loci mycobacterial interspersed repetitive units-variable numbers of tandem repeats (MIRU-VNTR24)...

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PMID: 36584485
DOI: 10.1016/j.tube.2022.102297

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