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Article

Whole-exome sequencing of Indian prostate cancer reveals a novel therapeutic target: POLQ.

Journal of cancer research and clinical oncology - 1 Jun 2023

Ravindran Febina, Jain Anika, Desai Sagar, Menon Navjoth, Srivastava Kriti, Bawa Pushpinder Singh, Sateesh K, Srivatsa N, Raghunath S K, Srinivasan Subhashini, Choudhary Bibha

Abstract excerpt

PURPOSE: Prostate cancer is the second most common cancer diagnosed worldwide and the third most common cancer among men in India. This study's objective was to characterise the mutational landscape of Indian prostate cancer using whole-exome sequencing to identify population-specific polymorphisms. METHODS: Whole-exome sequencing was performed of 58 treatment-naive primary prostate tumors of Indian origin....

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DNA-Directed DNA Polymerase
DNA Repair Enzymes
Exome Sequencing
Mutation
Pilot Projects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostate Cancer Treatment and Research

Prostatic Neoplasms

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PMID: 35737091
DOI: 10.1007/s00432-022-04111-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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