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ELSSI: parallel SNP-SNP interactions detection by ensemble multi-type detectors.

Briefings in bioinformatics - 18 Jul 2022

Wang Xin, Cao Xia, Feng Yuantao, Guo Maozu, Yu Guoxian, Wang Jun

Abstract excerpt

With the development of high-throughput genotyping technology, single nucleotide polymorphism (SNP)-SNP interactions (SSIs) detection has become an essential way for understanding disease susceptibility. Various methods have been proposed to detect SSIs. However, given the disease complexity and bias of individual SSI detectors, these single-detector-based methods are generally unscalable for real genome-wide...

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PMID: 35696639
DOI: 10.1093/bib/bbac213

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