Increased Cleavage of Japanese Encephalitis Virus prM Protein Promotes Viral Replication but Attenuates Virulence

Abstract excerpt

Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis epidemics in Southeast Asia, affecting mostly children, with high morbidity and mortality. During the viral maturation process, prM is cleaved into M by the cellular endoprotease furin in the acidic secretory system.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mosquito-borne diseases and control
• Share to Plant Virus Research Studies
• Share to Viral Infections and Vectors