Article
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage
16 Mar 2021
Abstract excerpt
Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by Japanese encephalitis virus. During the virus infection of the central nervous system, reactive gliosis, uncontrolled inflammatory response, and neuronal cell death are considered as the characteristic features of JE. To date, no specific treatment has been approved to overcome JE, indicating a need for the development of novel...
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