Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma

doi:10.1182/bloodadvances.2022007493

Article

Single-cell spatial analysis of tumor immune architecture in diffuse large B-cell lymphoma

8 Jun 2022

Abstract excerpt

Multiplexed immune cell profiling of the tumor microenvironment (TME) in cancer has improved our understanding of cancer immunology, but complex spatial analyses of tumor-immune interactions in lymphoma are lacking. Here, we used imaging mass cytometry (IMC) on 33 cases of diffuse large B-cell lymphoma (DLBCL) to characterize tumor and immune cell architecture and correlate it to clinicopathological features such...

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