On the prospect of achieving accurate joint estimation of selection with population history.

Abstract excerpt

As both natural selection and population history can affect genome-wide patterns of variation, disentangling the contributions of each has remained as a major challenge in population genetics. We here discuss historical and recent progress towards this goal-highlighting theoretical and computational challenges that remain to be addressed, as well as inherent difficulties in dealing with model complexity and model...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Variation
• Share to Genetics, Population