Article
In brief: cell senescence.
The Journal of pathology - 1 Jul 2013
Coates Philip J
Abstract excerpt
Cellular senescence is a key process that limits cancer development. The basics of our current understanding of the process are presented, including the genetic and epigenetic events that lead to the senescent phenotype. In addition to limiting replicative lifespan, senescence appears to act as a potent signal to activate immune clearance and alter the microenvironment. Finally, senescence induction is an area...
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