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SMYD2 aggravates gastrointestinal stromal tumor via upregulation of EZH2 and downregulation of TET1

6 Jun 2022

Abstract excerpt

SMYD2, as an oncogene, has been involved in multiple types of cancer, but the potential role of SMYD2 in gastrointestinal stromal tumors (GIST) remains enigmatic and requires further investigation. Hence, this study was conducted with the main objective of analyzing the effect of SMYD2 on GIST. GIST and adjacent normal tissues were collected from 46 patients with GIST where the expression of EZH2, SMYD2, and TET1...

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PMID: 35668081
DOI: 10.1038/s41420-022-01038-w

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