Article
Introduction of mutant TP53 related genes in metabolic pathways and evaluation their correlation with immune cells, drug resistance and sensitivity.
Life sciences - 15 Aug 2022
Motlagh Ali Valipour, Mahdevar Mohammad, Mirzaei Sepideh, Entezari Maliheh, Hashemi Mehrdad, Hushmandi Kiavash, Peymani Maryam
Abstract excerpt
BACKGROUND: Although the relationship between TP53 mutation, TP53 metabolism pathways, and tumorigenesis has been investigated, pan-cancer analysis of TP53 mutations and related metabolism pathways is not completely available in common types of human cancers. Thus, this study was going to represent TP53 mutant-related metabolism genes and pathways in a pan-cancer study and investigate the relationship between...
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