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A novel prognostic model for hepatocellular carcinoma based on pyruvate metabolism-related genes

16 Jun 2023

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, accounting for over 90% of cases. As pyruvate metabolic pathways are often dysregulated in cancer cells, investigating pyruvate metabolism-related genes may help identify prognostic gene signature and develop potential strategies for the management of patients with HCC. The mRNA expression profile, gene mutation data, and clinical...

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PMID: 37328616
DOI: 10.1038/s41598-023-37000-8

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