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Enhanced cobalamin biosynthesis in Ensifer adhaerens by regulation of key genes with gradient promoters

4 May 2022

Abstract excerpt

Cobalamin is an essential human vitamin widely used in the pharmaceutical, food, and feed additive industries and currently produced by bacteria or archaea. Ensifer adhaerens HY-1 is an industrial strain that also produces cobalamin. However production outputs are poor and the specific synthesis pathways require characterization. In this study, the whole genome sequence of E. adhaerens HY-1 was generated and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35664931
DOI: 10.1016/j.synbio.2022.04.012

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