Article
Shared environment and colorectal cancer: A Nordic pedigree registry-based cohort study.
International journal of cancer - 15 Oct 2022
Elmahdi Rahma, Wennerström Elna C M, Andersson Mikael, Wohlfahrt Jan, Melbye Mads, Pukkala Eero, Hortlund Maria, Silander Kaisa, Sutinen Kyösti, Jess Tine, Dillner Joakim
Abstract excerpt
Risk of colorectal cancer (CRC) increases in relatives of patients with CRC. The extent to which this is attributable to genetic predisposition or shared environment is unclear. We explored this question using nationwide cohorts from Denmark, Finland and Sweden. From 1977 to 2013, we identified 359 879 individuals with a CRC diagnosis and 2 258 870 of their relatives who we followed for CRC incidence. We...
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