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Article

Early-onset colorectal cancer risk extends to second- and third-degree relatives.

Cancer epidemiology - 1 Aug 2021

Ochs-Balcom Heather M, Kanth Priyanka, Cannon-Albright Lisa A

Abstract excerpt

INTRODUCTION: Family history is a risk factor for colorectal cancer (CRC), however whether family history also contributes to non-syndromic early-onset CRC is unknown. METHODS: We estimated risk to first-, second-, and third-degree relatives of early-onset CRC cases in the Utah Pedigree Database. RESULTS: We observed elevated risks beyond RR = 2.0 for early-onset CRC among first- and second-degree relatives of...

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Identifiers

PMID: 34198235
DOI: 10.1016/j.canep.2021.101973
PMCID: PMC8316419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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