Article
Preparation and Curation of Phenotypic Datasets.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022
Alvarez Prado Santiago, Hernández Fernando, Achilli Ana Laura, Amelong Agustina
Abstract excerpt
Based on case studies, in this chapter we discuss the extent to which the number and identity of quantitative trait loci (QTL) identified from genome-wide association studies (GWAS) are affected by curation and analysis of phenotypic data. The chapter demonstrates through examples the impact of (1) cleaning of outliers, and of (2) the choice of statistical method for estimating genotypic mean values of phenotypic...
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