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BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis

31 May 2022

Abstract excerpt

BACKGROUND: The key oncogene B-cell lymphoma 6 (BCL6) drives malignant progression by promoting proliferation, overriding DNA damage checkpoints and blocking cell terminal differentiation. However, its functions in the placenta and the endometrium remain to be defined. OBJECTIVE AND RATIONALE: Recent studies provide evidence that BCL6 may play various roles in the human placenta and the endometrium. Deregulated...

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PMID: 35640966
DOI: 10.1093/humupd/dmac027

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