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Mutation in Hemagglutinin Antigenic Sites in Influenza A pH1N1 Viruses from 2015-2019 in the United States Mountain West, Europe, and the Northern Hemisphere.

Genes - 19 May 2022

Decker Craig H, Rapier-Sharman Naomi, Pickett Brett E

Abstract excerpt

H1N1 influenza A virus is a respiratory pathogen that undergoes antigenic shift and antigenic drift to improve viral fitness. Tracking the evolutionary trends of H1N1 aids with the current detection and the future response to new viral strains as they emerge. Here, we characterize antigenic drift events observed in the hemagglutinin (HA) sequence of the pandemic H1N1 lineage from 2015-2019. We observed the...

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Identifiers

PMID: 35627294
DOI: 10.3390/genes13050909
PMCID: PMC9141826

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