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A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus

1 Jun 2010

Abstract excerpt

As the 2009 (H1N1) influenza A virus continues evolving, most mutations appear geographically and temporally confined. However, the latest surveillance data suggests emergence of a new prominent mutation, E391K, in the hemagglutinin (HA) that is globally on the rise. Interestingly, when modelled in the context of the available HA crystal structure, this mutation could alter salt bridge patterns and stability in a...

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PMID: 20535229
DOI: 10.1371/currents.rrn1162

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