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Article

Avian influenza A H5N1 hemagglutinin protein models have distinct structural patterns re-occurring across the 1959-2023 strains.

Bio Systems - 1 Dec 2024

Cueno Marni E, Kamio Noriaki, Imai Kenichi

Abstract excerpt

Influenza A H5N1 hemagglutinin (HA) plays a crucial role in viral pathogenesis and changes in the HA receptor binding domain (RBD) have been attributed to alterations in viral pathogenesis. Mutations often occur within the HA which in-turn results in HA structural changes that consequently contribute to protein evolution. However, the possible occurrence of mutations that results to reversion of the HA protein...

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Identifiers

PMID: 39349133
DOI: 10.1016/j.biosystems.2024.105347

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