Article
The Causal Relationship of Circulating Triglyceride and Glycated Hemoglobin: A Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism - 1 Mar 2020
Hsiung Chia-Ni, Chang Yi-Cheng, Lin Chien-Wei, Chang Chia-Wei, Chou Wen-Cheng, Chu Hou-Wei, Su Ming-Wei, Wu Pei-Ei, Shen Chen-Yang
Abstract excerpt
CONTEXT: The association between circulating triglyceride (TG) and glycated hemoglobin A1c (HbA1c), a biomarker for type 2 diabetes, has been widely addressed, but the causal direction of the relationship is still ambiguous. OBJECTIVE: To confirm the causal relationship between TG and HbA1c by using bidirectional and 2-step Mendelian randomization (MR) approaches. METHODS: We carried out a bidirectional MR...
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