Article
Mitochondrial Dysfunction and Chronic Inflammation in Polycystic Ovary Syndrome.
International journal of molecular sciences - 10 Apr 2021
Dabravolski Siarhei A, Nikiforov Nikita G, Eid Ali H, Nedosugova Ludmila V, Starodubova Antonina V, Popkova Tatyana V, Bezsonov Evgeny E, Orekhov Alexander N
Abstract excerpt
Polycystic ovarian syndrome (PCOS) is the most common endocrine-metabolic disorder affecting a vast population worldwide; it is linked with anovulation, mitochondrial dysfunctions and hormonal disbalance. Mutations in mtDNA have been identified in PCOS patients and likely play an important role in PCOS aetiology and pathogenesis; however, their causative role in PCOS development requires further investigation. As...
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