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Article

Successful restoration of archived ovine formalin fixed paraffin-embedded tissue DNA and single nucleotide polymorphism analysis.

Veterinary research communications - 1 Jan 2023

Kravitz Amanda, Tyler Ron, Manohar B Murali, Ronald B Samuel Masilamoni, Collins Michael T, Sriranganathan Nammalwar

Abstract excerpt

Archived formalin fixed paraffin-embedded (FFPE) tissues are powerful tools in medicine, capable of harboring diagnostic and genetic answers to challenging clinical questions. Successful utilization of DNA derived from FFPE samples is dependent upon repairing DNA damage generated from the fixation process. Methods to repair FFPE DNA have been successful in human medicine for a variety of research and clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35618986
DOI: 10.1007/s11259-022-09937-0
PMCID: PMC9873697

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