Article
Retrospective Single Nucleotide Polymorphism Analysis of Host Resistance and Susceptibility to Ovine Johne's Disease Using Restored FFPE DNA.
International journal of molecular sciences - 15 Jul 2024
Kravitz Amanda, Liao Mingsi, Morota Gota, Tyler Ron, Cockrum Rebecca, Manohar B Murali, Ronald B Samuel Masilamoni, Collins Michael T, Sriranganathan Nammalwar
Abstract excerpt
Johne's disease (JD), also known as paratuberculosis, is a chronic, untreatable gastroenteritis of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP) infection. Evidence for host genetic resistance to disease progression exists, although it is limited due to the extended incubation period (years) and diagnostic challenges. To overcome this, previously restored formalin-fixed paraffin embedded...
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