Article
Plasma MicroRNAs as noninvasive diagnostic biomarkers in patients with Brugada syndrome.
PloS one - 1 Jan 2022
Ikeuchi Yoshihiro, Ochi Hidenori, Motoda Chikaaki, Tokuyama Takehito, Okubo Yousaku, Okamura Sho, Miyauchi Syunsuke, Miyamoto Shogo, Uotani Yukimi, Onohara Yuko, Nakashima Mika, Akiyama Rie, Tahara Hidetoshi, Chayama Kazuaki, Kihara Yasuki, Nakano Yukiko
Abstract excerpt
BACKGROUND: Brugada syndrome (BrS) can be diagnosed by a type 1 BrS tracing in a 12-lead electrocardiogram (ECG). However, there are daily variations in the ECGs of BrS patients, which presents a challenge when diagnosing BrS. Although many susceptibility genes have been identified, the SCN5A gene is reportedly the main causative gene of BrS. However, most patients do not have an evidence of genetic...
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