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Article

miR-223 Exerts Translational Control of Proatherogenic Genes in Macrophages

25 May 2022

Abstract excerpt

Background: A significant burden of atherosclerotic disease is driven by inflammation. Recently, microRNAs (miRNAs) have emerged as important factors driving and protecting from atherosclerosis. miR-223 regulates cholesterol metabolism and inflammation via targeting both cholesterol biosynthesis pathway and NF k B signaling pathways; however, its role in atherosclerosis has not been investigated. We hypothesize...

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PMID: 35611698
DOI: 10.1161/circresaha.121.319120

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