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Article

Aberrant Multiciliogenesis in Idiopathic Pulmonary Fibrosis

24 May 2022

Abstract excerpt

Abstract We previously identified a novel molecular subtype of idiopathic pulmonary fibrosis (IPF) defined by increased expression of cilium-associated genes, airway mucin gene MUC5B, and KRT5 marker of basal cell airway progenitors. Here we show the association of MUC5B and cilia gene expression in human IPF airway epithelial cells, providing further rationale for examining the role of cilium genes in the...

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Identifiers

PMID: 35608953
DOI: 10.1165/rcmb.2021-0554oc

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