Article
Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs.
Respiratory research - 16 Jul 2016
Smirnova N F, Schamberger A C, Nayakanti S, Hatz R, Behr J, Eickelberg O
Abstract excerpt
BACKGROUND: In the human lung, epithelial progenitor cells in the airways give rise to the differentiated pseudostratified airway epithelium. In mice, emerging evidence confers a progenitor function to cytokeratin 5 (KRT5(+)) or cytokeratin 14 (KRT14(+))-positive basal cells of the airway epithelium. Little is known, however, about the distribution of progenitor subpopulations in the human lung, particularly...
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