Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emergence of hybrid states of stem-like cancer cells correlates with poor prognosis in oral cancer

28 Apr 2022

Abstract excerpt

Cancer cell state transitions emerged as powerful mechanisms responsible for drug tolerance and overall poor prognosis; however, evidences were largely missing in oral cancer. Here, by multiplexing phenotypic markers of stem-like cancer cells (SLCCs); CD44, CD24 and aldehyde dehydrogenase (ALDH), we characterized diversity among multiple oral tumor tissues and cell lines. Two distinct patterns of spontaneous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Cancer, Hypoxia, and Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35602941
DOI: 10.1016/j.isci.2022.104317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emergence of hybrid states of stem-like cancer cells correlates with poor prognosis in oral cancerPMID 35602941Read ↗

Spontaneous differentiation leads to emergence of hybrid cell states relate to poor prognosis in oral cancerSemantic proximity Read ↗

Single‐Cell Transcriptome Analysis Uncovers Intratumoral Heterogeneity and Underlying Mechanisms for Drug Resistance in Hepatobiliary Tumor OrganoidsSemantic proximity Read ↗

Tumor heterogeneity from the viewpoint of pathologists.Semantic proximity Read ↗

Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinomaSemantic proximity Read ↗

Cancer stem cell plasticity and its implications in the development of new clinical approaches for oral squamous cell carcinomaSemantic proximity Read ↗

Advancement in Cancer Stem Cell Biology and Precision Medicine—Review Article Head and Neck Cancer Stem Cell Plasticity and the Tumor MicroenvironmentSemantic proximity Read ↗

The Concept of Cancer Stem Cells: Elaborating on ALDH1B1 as an Emerging Marker of Cancer ProgressionSemantic proximity Read ↗

Genomic and Single-Cell Analyses Characterize Patient-Derived Tumor Organoids to Enable Personalized Therapy for Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Drug-Tolerant Persister Cells in Cancer Therapy ResistanceSemantic proximity Read ↗

Identification of Phenotypically Distinct Cancer Stem Cell Subpopulations in Oral Squamous Cell CarcinomaSemantic proximity Read ↗

Stochastic Population Dynamics of Cancer Stemness and Adaptive Response to TherapiesSemantic proximity Read ↗

Heterogeneity of normal human breast stem and progenitor cells as revealed by transcriptional profilingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.