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Article

TLR4 regulatory region variants reduce the susceptibility of small-cell lung cancer in Chinese population.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jul 2022

Zhang Hongmei, Gao Hui, Li Ang, Wu Hongjiao, Xie Yuning, Zhang Zhi, Zhang Xuemei

Abstract excerpt

OBJECTIVES: Toll-like receptors (TLRs) participate in the induction and regulation of immune responses and are closely related to the occurrence and development of small-cell lung cancer (SCLC). This study aimed to investigate the impact of polymorphisms in the regulatory regions of TLRs on the susceptibility of SCLC. METHODS: The case-control study included 304 SCLC patients and 304 healthy controls. TLRs gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35579180
DOI: 10.1097/CEJ.0000000000000737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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