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Article

Determination of the Relationship Between rs4986790 and rs4986791 Variants of TLR4 Gene and Lung Cancer.

Inflammation - 1 Feb 2016

Kurt Hulyam, Ozbayer Cansu, Bayramoglu Aysegul, Gunes Hasan Veysi, Degirmenci İrfan, Oner Kevser Setenay, Metintas Muzaffer

Abstract excerpt

Chronic inflammation triggers DNA damage and oncogenic mutations and causes tumor formation and tumor progression. One of the important components of the inflammatory response is Toll-like receptor (TLR) family. The objective of our study is to determine the relationship between rs4986790(+896A/G) and rs4986791(+1196C/T) gene polymorphisms and lung cancer risk. PCR-RFLP technique was carried out to identify the...

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Source

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PMID: 26299699
DOI: 10.1007/s10753-015-0235-9

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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