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The Roles of Histone Deacetylases in the Regulation of Ovarian Cancer Metastasis

11 Oct 2023

Abstract excerpt

Ovarian cancer is the most lethal gynecologic malignancy, and metastasis is the major cause of death in patients with ovarian cancer, which is regulated by the coordinated interplay of genetic and epigenetic mechanisms. Histone deacetylases (HDACs) are enzymes that can catalyze the deacetylation of histone and some non-histone proteins and that are involved in the regulation of a variety of biological processes...

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PMID: 37894746
DOI: 10.3390/ijms242015066

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