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Article

The rs483145 polymorphism of MC4R gene is not associated with obesity in the Chilean population: Results of GENADIO study.

Endocrinologia, diabetes y nutricion - 1 Apr 2022

Mardones Lorena, Parra-Valencia Esteban, Petermann-Rocha Fanny, Martínez-Sanguinetti María Adela, Leiva-Ordoñez Ana María, Lasserre-Laso Nicole, Martorell Miquel, Ulloa Natalia, Sanhueza Eduardo, Pérez-Bravo Francisco, Celis-Morales Carlos, Villagrán Marcelo

Abstract excerpt

INTRODUCTION: The melanocortin receptor 4 (MC4R) participates in the control of appetite at the level of the central nervous system, through the leptin-melanocortin pathway. An association between different polymorphisms of the MC4R gene and obesity has been reported. However, there are few studies of the rs483145 single nucleotide polymorphism (SNP) of this gene. OBJECTIVE: To investigate its prevalence and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35570141
DOI: 10.1016/j.endien.2022.03.004

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