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Whole Genome Amplification in Preimplantation Genetic Testing in the Era of Massively Parallel Sequencing

27 Apr 2022

Abstract excerpt

Successful whole genome amplification (WGA) is a cornerstone of contemporary preimplantation genetic testing (PGT). Choosing the most suitable WGA technique for PGT can be particularly challenging because each WGA technique performs differently in combination with different downstream processing and detection methods. The aim of this review is to provide insight into the performance and drawbacks of DOP-PCR, MDA...

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PMID: 35563216
DOI: 10.3390/ijms23094819

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