Article
Detection of macrolide and fluoroquinolone resistance-associated 23S rRNA and parC mutations in Mycoplasma genitalium by nested real-time PCR.
Frontiers in cellular and infection microbiology - 1 Jan 2023
He Wenyin, Yuan Ying, Liang Junyu, Fan Xuejiao, Li Lei, Pan Xingfei
Abstract excerpt
Background: Traditional drug susceptibility testing cannot be performed in clinical laboratories due to the slow-growing characteristics of Mycoplasma genitalium when cultured in vitro. Sanger sequencing is the standard method for detecting drug resistance-associated mutations. It has been used in some laboratories to guide the choice of macrolide antibiotics for Mycoplasma genitalium infected patients....
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