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Epigenetics and pulmonary diseases in the horizon of precision medicine: a review

19 Nov 2020

Abstract excerpt

Epigenetic mechanisms represent potential molecular routes which could bridge the gap between genetic background and environmental risk factors contributing to the pathogenesis of pulmonary diseases. In patients with COPD, asthma and pulmonary arterial hypertension (PAH), there is emerging evidence of aberrant epigenetic marks, mainly including DNA methylation and histone modifications which directly mediate...

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PMID: 33214212
DOI: 10.1183/13993003.03406-2020

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