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Gut bacteria signaling to mitochondria in intestinal inflammation and cancer

26 Mar 2019

Abstract excerpt

The gastrointestinal microbiome plays a pivotal role in physiological homeostasis of the intestine as well as in the pathophysiology of diseases including inflammatory bowel diseases (IBD) and colorectal cancer (CRC). Emerging evidence suggests that gut microbiota signal to the mitochondria of mucosal cells, including epithelial cells and immune cells. Gut microbiota signaling to mitochondria has been shown to...

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PMID: 30913966
DOI: 10.1080/19490976.2019.1592421

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