Article
rs3806265 and rs4612666 of the NLRP3 Gene Are Associated With the Titer of Glutamic Acid Decarboxylase Antibody in Type 1 Diabetes.
Frontiers in endocrinology - 1 Jan 2022
Sun Xiaoxiao, Xu Linling, Xia Ying, Luo Shuoming, Lin Jian, Xiao Yang, Huang Gan, Li Xia, Xie Zhiguo, Zhou Zhiguang
Abstract excerpt
Background and Aims: The NLRP3 gene is reportedly associated with several autoimmune diseases. However, in the Chinese Han population, whether NLRP3 polymorphisms are associated with type 1 diabetes (T1D) is unclear. Therefore, this study examined the associations of rs3806265 and rs4612666 of the NLRP3 gene with T1D susceptibility and the clinical characteristics of Chinese Han T1D patients. Methods: In total,...
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