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Article

Analysis of senescence in gingival tissues and gingival fibroblast cultures

2 May 2022

Abstract excerpt

OBJECTIVE: To determine senescence-associated changes in the gingival tissues of aged mice and gingival fibroblast cultures. MATERIALS AND METHODS: The production of senescence-associated β-galactosidase (SA-β-gal) and mRNA expression of p16, p21, interleukin (IL)-1β, and tumor necrosis factor α (TNF-α) were evaluated in gingival tissues, gingival fibroblasts of 10- and 20-month-old C57BL/6NCrl mice, and...

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PMID: 35491709
DOI: 10.1002/cre2.581

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