Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fusobacterium nucleatum triggers senescence phenotype in gingival epithelial cells.

Molecular oral microbiology - 1 Apr 2024

Albuquerque-Souza Emmanuel, Shelling Benjamin, Jiang Min, Xia Xia-Juan, Rattanaprukskul Kantapon, Sahingur Sinem Esra

Abstract excerpt

The prevalence of periodontitis increases with physiological aging. However, whether bacteria associated with periodontal diseases foster aging and the mechanisms by which they may do so are unknown. Herein, we hypothesize that Fusobacterium nucleatum, a microorganism associated with periodontitis and several other age-related disorders, triggers senescence, a chief hallmark of aging responsible to reduce tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Senescence
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Lamins

Share to Periodontitis

Share to Phenotype

Share to Tumor Suppressor Protein p14ARF

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 37718958
DOI: 10.1111/omi.12432
PMCID: PMC10939983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fusobacterium nucleatum triggers senescence phenotype in gingival epithelial cells.PMID 37718958Read ↗

Molecular Signatures of Senescence in Periodontitis: Clinical InsightsSemantic proximity Read ↗

Beyond the Hayflick limit: How microbes influence cellular agingSemantic proximity Read ↗

Transcriptome profiling analysis of senescent gingival fibroblasts in response to Fusobacterium nucleatum infectionSemantic proximity Read ↗

Cellular Senescence and Periodontitis: Mechanisms and TherapeuticsSemantic proximity Read ↗

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Induces Cellugyrin-(Synaptogyrin 2) Dependent Cellular Senescence in Oral KeratinocytesSemantic proximity Read ↗

Evaluating the effect of LPS from periodontal pathogenic bacteria on the expression of senescence‐related genes in human dental pulp stem cellsSemantic proximity Read ↗

TitleBiological Effects of “Inflammageing” on Human Oral Cells: Insights into a Potential Confounder of Age-Related DiseasesSemantic proximity Read ↗

Senescence and Host–Pathogen InteractionsSemantic proximity Read ↗

Impact of Periodontitis and Oral Dysbiosis Metabolites in the Modulation of Accelerating Ageing and Human SenescenceSemantic proximity Read ↗

Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissueSemantic proximity Read ↗

Immune senescence and periodontitis: From mechanism to therapySemantic proximity Read ↗

Virulence Factors of the Periodontal Pathogens: Tools to Evade the Host Immune Response and Promote CarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.