Article
Intra-host genetic population diversity: Role in emergence and persistence of drug resistance among Mycobacterium tuberculosis complex minor variants.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2022
Vázquez-Chacón Carlos Arturo, de Jesús Rodríguez-Gaxiola Felipe, Sánchez-Flores Alejandro, Montaño Sarita, Bello-Rios Ciresthel, Fonseca-Coronado Salvador, López-Carrera Cruz Fernando, Martínez-Guarneros Armando, Parra-Unda Ricardo, García-Magallanes Noemí, Arámbula-Meraz Eliakym, Escobar-Gutiérrez Alejandro, Cruz-Rivera Mayra, López-Durán Paúl Alexis
Abstract excerpt
Drug resistant tuberculosis (DR-TB) is an important public health issue in different parts of the world. Mycobacterium tuberculosis complex variants (MTBC vars) preferentially infect certain hosts, limiting their distribution to different ecosystems. However, MTBC vars can infect other hosts beyond their preferred target potentially contributing to persistence of drug resistance (DR) in other niches. Here, we...
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